H2N2V1, Main, Exploration, bibRecord, 001774

Generation of influenza A virus from cloned cDNAs — historical perspective and outlook for the new millenium

Identifieur interne : 001774 ( Main/Exploration ); précédent : 001773; suivant : 001775

Generation of influenza A virus from cloned cDNAs — historical perspective and outlook for the new millenium

Auteurs : Gabriele Neumann [États-Unis] ; Yoshihiro Kawaoka [États-Unis, Japon]

Source :

Reviews in Medical Virology [ 1052-9276 ] ; 2002-01.

RBID : ISTEX:6EF5D84F5680A675659A4B539A43F4A829C310D6

English descriptors

Teeft :
- Acad, Amino acid, Attenuated, Avian, Brownlee, Castrucci, Cdna, Cell culture, Channel activity, Chimeric, Coding region, Copyright, Crna, Cytoplasmic, Cytoplasmic tail, Deletion, Embo, Enami, Encoding, Epitope, Eukaryotic cells, Fodor, Foreign protein, Fusion protein, Gene, Gene delivery, Genes encoding, Genetics, Genetics system, Genome, Glycoprotein, Glycosylation site, Helper virus, Hemagglutinin, Hobom, Hoffmann, Hong kong, Human virus type, Important role, Infectious viruses, John wiley sons, Kawaoka, Mammalian cells, Molecular basis, Mrna, Mutagenesis, Mutant, Mutation, Mutational analysis, Natl, Neumann, Neuraminidase, Noncoding, Noncoding regions, Nuclear export, Nucleoprotein, Nucleotide, Palese, Panhandle, Plasmid, Polyadenylation, Polyadenylation signal, Polymerase, Polymerase proteins, Polymerase system, Proc, Proc natl acad, Promoter, Promoter activity, Promoter region, Protein, Protein expression, Protein expression plasmids, Reassortant virus, Recombinant, Recombinant vaccinia virus, Recombinant virus, Recombinant viruses, Reconstitution, Replication, Reporter gene, Rna, Selection system, Selection systems, Seong, Terminal nucleotides, Terminator sequences, Transcription, Transfectant, Transfectant virus, Transfectant viruses, Transfected, Transfection, Transfection method, Transfection system, Uridine stretch, Vaccine, Vaccinia, Vero cells, Viral, Viral genome, Viral infection, Viral life cycle, Viral proteins, Viral replication, Viral rnas, Virion, Virol, Virology, Virus, Virus assembly, Virus generation, Virus hemagglutinin, Virus neuraminidase, Virus promoter, Virus replication, Virus vaccines, Vrna, Vrna synthesis, Vrnas, Vrnp, Vrnp complexes, Vrnps, Watanabe.

Abstract

Influenza virus reverse genetics has reached a level of sophistication where one can confidently generate virus entirely from cloned DNAs. The new systems makes it feasible to study the molecular mechanisms of virus replication and pathogenicity, as well as to generate attenuated live virus vaccines, gene delivery vehicles, and possibly other RNA viruses from cloned cDNAs. During the next decade, one can anticipate the translation of influenza virus reverse genetics into biomedically relevant advances. Copyright © 2002 John Wiley & Sons, Ltd.

Url:

https://api.istex.fr/ark:/67375/WNG-M3FD8QCM-5/fulltext.pdf

DOI: 10.1002/rmv.332

Affiliations:

Links toward previous steps (curation, corpus...)

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to stream Istex, to step Checkpoint: 000621
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Le document en format XML

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<term>Brownlee</term>
<term>Castrucci</term>
<term>Cdna</term>
<term>Cell culture</term>
<term>Channel activity</term>
<term>Chimeric</term>
<term>Coding region</term>
<term>Copyright</term>
<term>Crna</term>
<term>Cytoplasmic</term>
<term>Cytoplasmic tail</term>
<term>Deletion</term>
<term>Embo</term>
<term>Enami</term>
<term>Encoding</term>
<term>Epitope</term>
<term>Eukaryotic cells</term>
<term>Fodor</term>
<term>Foreign protein</term>
<term>Fusion protein</term>
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<term>Genome</term>
<term>Glycoprotein</term>
<term>Glycosylation site</term>
<term>Helper virus</term>
<term>Hemagglutinin</term>
<term>Hobom</term>
<term>Hoffmann</term>
<term>Hong kong</term>
<term>Human virus type</term>
<term>Important role</term>
<term>Infectious viruses</term>
<term>John wiley sons</term>
<term>Kawaoka</term>
<term>Mammalian cells</term>
<term>Molecular basis</term>
<term>Mrna</term>
<term>Mutagenesis</term>
<term>Mutant</term>
<term>Mutation</term>
<term>Mutational analysis</term>
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<term>Neumann</term>
<term>Neuraminidase</term>
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<term>Noncoding regions</term>
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<term>Nucleotide</term>
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<term>Plasmid</term>
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<term>Proc natl acad</term>
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<term>Promoter activity</term>
<term>Promoter region</term>
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<term>Protein expression plasmids</term>
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<term>Recombinant viruses</term>
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<term>Replication</term>
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<term>Rna</term>
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<term>Transfection</term>
<term>Transfection method</term>
<term>Transfection system</term>
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<term>Vero cells</term>
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<term>Viral genome</term>
<term>Viral infection</term>
<term>Viral life cycle</term>
<term>Viral proteins</term>
<term>Viral replication</term>
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<term>Virus neuraminidase</term>
<term>Virus promoter</term>
<term>Virus replication</term>
<term>Virus vaccines</term>
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<term>Vrna synthesis</term>
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<term>Vrnp</term>
<term>Vrnp complexes</term>
<term>Vrnps</term>
<term>Watanabe</term>
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<front><div type="abstract" xml:lang="en">Influenza virus reverse genetics has reached a level of sophistication where one can confidently generate virus entirely from cloned DNAs. The new systems makes it feasible to study the molecular mechanisms of virus replication and pathogenicity, as well as to generate attenuated live virus vaccines, gene delivery vehicles, and possibly other RNA viruses from cloned cDNAs. During the next decade, one can anticipate the translation of influenza virus reverse genetics into biomedically relevant advances. Copyright © 2002 John Wiley & Sons, Ltd.</div>
</front>
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Generation of influenza A virus from cloned cDNAs — historical perspective and outlook for the new millenium

Generation of influenza A virus from cloned cDNAs — historical perspective and outlook for the new millenium

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri